I use to use ad-block just because I couldn't be arsed to go through ads when I watched videos before I knew how ad-based sites went. Especially now that I was given the option to monetize on youtube and give proper respects to allow ads on sites that don't explode your face off with overplaced ads. Also ads with audio, seriously?
I don't need to have 3+ audio clips exploding my speakers/headphones when I want to look at art. As well as the fact that any art streamers who play music for their streams with have sudden clashing sound battles for whatever decides to play on that ad square on the bottom of the page. Let's stop the bleeding before you have another mass movement to the alternate art sites that have been put in play that you already lost people to.

I want to allow the ads as I know they cover the cost of the server space on some level. But I cannot say that the current ad layout, especially on the submission pages (so bad it overlaps flash files if they are big) is something that is going to win over anybody on this site. Ads should not pull the attention so strongly away from a site based around art.

If nothing else at least don't allow the audio ads to take over any space on a page. You have a section dedicated to music uploads. I shouldn't have to say how bad that ends up being if you try to listen on the page now without blocking the ads now.